GLP-1 for Weight Loss: Semiglutide & Ozempic Explained

GLP-1 (Glucagon-Like Peptide 1) is a gut-derived hormone that enhances insulin secretion, suppresses glucagon (which increases sugar production), slows gastric emptying, and reduces appetite. It interacts with the brain to signal fullness, making it a key factor in weight management. Medications like Semiglutide replicate GLP-1’s effects and have become widely used for weight loss.

Semiglutide was initially developed for type 2 diabetes but is now FDA-approved for weight loss under the brand name Ozempic. It is prescribed for individuals with a BMI over 30 or a BMI over 27 with obesity-related conditions. Due to high demand, compounded versions of Semiglutide are also available off-label. While this increases accessibility, it’s crucial to consider the associated risks and benefits.

Benefits of Semiglutide for Weight Loss

• Significant weight reduction when combined with diet and exercise
• Appetite suppression and reduced cravings
• Potential improvement in cardiovascular health and diabetes risk

Side Effects and Risks

While effective, Semiglutide has notable side effects, including:

• Common issues: Nausea, diarrhea, constipation, bloating, headaches
• Serious risks: Pancreatitis, gallbladder disease, kidney issues, rapid heart rate, and even depression
• Long-term considerations: Weight regain after stopping the medication; potential loss of muscle mass

Cost of Ozempic vs. Compounded Semiglutide

A major drawback is cost. Ozempic costs around $1,200 per month, while compounded Semiglutide is approximately $400 per month. Insurance coverage varies based on eligibility. Consulting a healthcare provider is essential for exploring affordable options.

Is GLP-1 Weight Loss Right for You?

If you’re considering GLP-1 weight loss options in Denver, speak with a medical weight loss specialist. While dieting alone may not always work, incorporating medications like Semiglutide can be a valuable tool—if used correctly and under supervision.

Take the Next Step

Interested in learning more? Schedule a consultation to discuss whether GLP-1 medications like Semiglutide or Ozempic are right for your weight loss journey.